Mechanism Of Action Of Lactulose
- Lactulose is a medication that belongs to a class of medicines called “laxatives”. It is used to help relieve
- constipation by making your stools softer and easier to pass. It works by drawing water into the intestines.
- It is also used for hepatic encephalopathy (a decline in brain function that occurs as a result of severe liver disease) by decreasing the amount of ammonia in the blood.
Non-Pharmacological Treatments & Advice To Reduce Constipation
- Drink more water
- Eat more fiber, especially soluble, non-fermentable fiber
- Exercise more
- Eat probiotic foods or take probiotic supplements
- Bowel habit training.
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Method Of Administration Of Duphalac Syrup
- Dosage in stool softening and constipation:
- Adults and adolescents: Recommended starting dose is 15 – 45 ml (10 – 30 g) followed by a maintenance dose of 15 – 30 ml (10 – 20 g).
- Children (7 – 14 years old): Recommended starting dose is 15 ml (10 g) followed by a maintenance dose of 10 – 15 ml (7 – 10 g).
- Children (1 – 6 years old): Recommended starting and maintenance dose is 5 – 10 ml (3 – 7 g).
- Infants under 1 year of age: Recommended starting and maintenance dose is up to 5 ml (up to 3 g).
- Dosage in hepatic encephalopathy (adults):
- The recommended initial dose is 30 – 45 ml orally three to four times daily followed by a maintenance dose that is adjusted depending on your response until you start producing 2 – 3 stools daily.
- The dose may be taken as a single daily dose or may be divided into two daily doses.
- You can use the measuring cup provided with the bottle to measure your dose.
- It may take a few days for the medication to start giving effect. A maintenance dose is specified based on your response.
- You may take the medication without regard to meals.
- Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
- If you take more than you should, talk to a doctor or go to the hospital straight away.
- If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
- Do not take a double dose (two doses at the same time) to make up for the forgotten dose.